Monday, 21 April 2014

Cell Reprogramming for Aging

As we age, the brain gets less efficient and forgetfulness increases by leaps and bounds. Acquiring Alzheimer’s disease or Parkinsonism is not the case always but certain other degenerative proteins cite actions that decrease the brain efficiency. It is the cholinergic and dopaminergic neurons that begin the deleterious effect on the memory. Since the cholinergic neurotransmitters govern the actions at the basal ganglia of the brain, the neurodegenerative changes through normal aging begin their action.

Along with aging, the brain cells start being damaged and give rise to various mental disorders. No such medication has been invented that may completely cure the following ailments but delay the process. Similarly, aging can never be stopped but the consequences can be slowed down.

In the article Gene Therapy and Cell Reprogramming For the Aging Brain: Achievements and Promise the author has discussed aging and the effects of cholinergic and dopaminergic agonists and antagonists in a vast perspective. The article also features modification of cells with age and the mal-effects on diabetic patients. The journal Current Gene Therapy focuses on the gene and cell therapy. Moreover, the research tells much about the experimental evidence supporting the neuroprotective relevance of these and related factors in the aging brain.


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