Cell Reprogramming for Aging

As we age, the brain gets less efficient and forgetfulness increases by leaps and bounds. Acquiring Alzheimer’s disease or Parkinsonism is not the case always but certain other degenerative proteins cite actions that decrease the brain efficiency. It is the cholinergic and dopaminergic neurons that begin the deleterious effect on the memory. Since the cholinergic neurotransmitters govern the actions at the basal ganglia of the brain, the neurodegenerative changes through normal aging begin their action.

Along with aging, the brain cells start being damaged and give rise to various mental disorders. No such medication has been invented that may completely cure the following ailments but delay the process. Similarly, aging can never be stopped but the consequences can be slowed down.

In the article Gene Therapy and Cell Reprogramming For the Aging Brain: Achievements and Promise the author has discussed aging and the effects of cholinergic and dopaminergic agonists and antagonists in a vast perspective. The article also features modification of cells with age and the mal-effects on diabetic patients. The journal Current Gene Therapy focuses on the gene and cell therapy. Moreover, the research tells much about the experimental evidence supporting the neuroprotective relevance of these and related factors in the aging brain.

Continue

Sleep Apnea: Obstructive Sleep Apnea (OSA)

Sleep apnea is a common condition, in which a person has problem in breathing. Obstructive Sleep Apnea is one of the most common types of sleep apnea. It is caused by obstruction of the upper respiratory tract. This form of sleep apnea is characterized by recurring pauses in breathing during sleeping. This obstruction happens, most commonly, due to a reduction in blood oxygen saturation.

Its major signs and symptoms include loud and continual snoring. Other symptoms are:

• Morning headaches
• Memory or learning problems and not being able to concentrate
• Feeling irritable, depressed, or having mood swings or personality changes
• Waking up frequently to urinate
• Dry mouth or sore throat when you wake up

There are three kinds of Sleep Apnea;

1. Central Sleep Apnea (CSA)
2. Obstructive Sleep Apnea (OSA)
3. Complex Sleep Apnea (Combination of Complex and Obstructive)

CSA happens due to insufficient respiratory effort. On the other hand, Complex sleep apnea is a mixture of both OSA and CSA.

Regardless of the fact that Sleep Apnea occurs regardless of age and gender, yet OSA is much common in females. The topic “Influence of Gender on C-Reactive Protein, Fibrinogen, and Erythrocyte Sedimentation Rate in Obstructive Sleep Apnea” by Bentham Science Publishers discusses the details regarding protein bindings with fibrinogens and erythrocytes sedimentation rates. Their research provides adequate information based on CRP and fibrinogen level. They also explain the systemic inflammatory markers relating it with female physiological activity that supports OSA more in females than males.

Continue

Air Pollution and Hypertension

Breathing in smoke increases the risk of developing lethal complications like, asthma, preeclampsia and other infections. Moreover, studies have suggested that there is a link between reduced birth rates of infants and exposure to air pollution.

Air pollution jeopardizes the health of humans and damages the ecosystem. According to the recent standards, a large part of the whole population is not living in a healthy environment.

However, breathing in polluted environment can be as harmful to the pregnant women, as inhaling a cigarette smoke. Another study suggested that, the considerable percentage of cases of low birth weight could be easily prevented if the air pollution is reduced. According to the recent findings, exposure to the air pollutants can lead to extensive risk for developing high blood pressure at some point in your pregnancy.

There are numerous pollutants that are found in air pollution but the two basic types of pollutants include sulfur dioxide and carbon monoxide. Other pollutants include dust, acid, soil particles and metals. All these pollutants are inhalable and released from forest fires and industries. On the other hand, carbon monoxide is released from the car exhaust, and sulfur dioxide is produced from industries and power plants.

According to, Xiaohui Xu, M.D., Ph.D., an assistant professor of epidemiology in the colleges of Public Health and Health Professions and Medicine; "That is why we wanted to do this research. Hypertension (high blood pressure), in particular, is associated with increased morbidity and mortality, causing a lot of problems for the mother and fetus, including preterm delivery."

Bentham Science Publishers is a renowned publisher in the industry with almost 300+ journals and open access journals and numerous eBooks in almost all fields of science. For more details about Bentham science Publishers, visit: www.benthamscience.com.

Continue

Bentham eBooks: The Whole Story behind Blind Adaptive Equalizers/ Blind Deconvolution

Bentham Science aims to publish eBooks in all major areas of technology, social sciences, medicine and humanities. Their eBooks provide professionals, corporate researchers, academicians, graduates and under-graduates globally with the most contemporary information in their subject areas of interest.

It is well known that Intersymbol (ISI) Interference is a limiting factor in many communication environments where it causes an irreducible degradation of the bit error rate (BER) thus imposing an upper limit on the data symbol rate. In order to overcome the ISI problem, an equalizer is implemented in those systems. Among the three types of equalizers - non-blind, semi-blind and blind – the blind equalizer has the benefit of bandwidth saving and there is no need of going through a training phase. Blind equalization algorithms are essentially adaptive filtering algorithms designed such that they do not require the external supply of a desired response to generate the error signal in the output of the adaptive equalization filter. The algorithms generate an estimate of the desired response by applying a nonlinear transformation to sequences involved in the adaptation process. This nonlinearity is designed to minimize a cost function that is implicitly based on higher order statistics (HOS) according to one approach, or calculated directly according to the Bayes rules.

The complete review is available on:

http://www.benthamscience.com/ebooks/9781608053520/index.htm

Continue

Psoriasis-An acute medical condition:

Psoriasis is an acute skin condition which causes scaling and inflammation problems. This abnormality is developed as a result of the body`s immune system. It is a hereditary condition and majority of the patients have a family history of this medical disorder. This disease is also triggered by the usage of certain drugs.

The major symptoms of this disease include itching and skin inflammation. There are various types of Psoriasis like inverse psoriasis, plaque psoriasis and pustular psoriasis. It occurs internally before it appears on the skin.

It can diagnosed with the help of skin and nail analysis. Sometimes skin biopsy is recommended by the doctors who confirm the diagnosis and rules out various probable skin disorders.

Some of the treatments of this disorder include daily skin lubrication, oral medication, laser therapies and various biological therapies.

Bentham Science Publishers is a remarkable name in the STM publishing industry. An eBook “Dermatological Treatments”  is available on http://benthamscience.com/ related to skin related conditions.

Continue

Mood Disorders

There comes a point in everyone’s life, when they experiences the ‘ups’ and ‘downs’ but a few people with a mood disorder experience it with a higher intensity and for a much longer time period. The condition that mood disorders cause to people includes a feeling of; depression, disturbed physical health, prolonged emotions that depressingly affects people mentally.

Depression and bipolar disorder which is known as manic depression are both serious medical illnesses but are treatable. The people who have bipolar disorder, experiences depression and usually feels really high. The ‘highs’ get uncontrolled and manic person behave in a hasty manner.

Depression- the most common mood disorder in which is person feels very low. The symptoms may include, tiredness, altered eating patterns, sleeping problems, hopelessness, thoughts of suicide and an incapability to have fun. These mood disorders can be treated through counseling, but in extreme cases, proper medical assistance is advised.

Bentham Science Publishers covers a variety of topics in the fields of science, technology, medicine, natural sciences and social sciences. Here is one of its eBook that incorporates discourse related to mood disorders. You can click here to for more information about this eBook: http://www.benthamscience.com/ebooks/9781608054671/index.htm

For more eBooks, visit: http://www.benthamscience.com/ebooks/index.htm

Continue

Intermittent Explosive Disorder and Chronic Inflammation

Displays of aggressive outbursts portray a mental illness known as the Intermittent Explosive Disorder. This disorder, unfortunately, is also believed to be linked with inflammation, according to a blood test analysis by researchers.

Inflammation is the term used to describe the body’s effort to keep it safe from the attacks of pathogens. When body is threatened, it reacts by inflating the particular body part, and begins the healing process.’ [You can find out more about inflammation at http://benthamsciencepublishers.blogspot.com/2013/12/inflammation-innate-immune-system.html

In fact, according to a study by Dr. Stephen H Boyle of Duke University Medical Center in Durham, North Carolina, recurring outbursts of anger might have a biological basis. People who have been diagnosed with this condition suffer repeated episodes of aggressive behavior.  They often lose control over trivial things and react with violent outbursts, like hurting people physically, throwing things around and vandalizing property.

Researchers and scientists advocate that increased levels of C-reactive protein and Interleukin-6 are indicators of possible inflammation in blood. These two are also believed to have strong connection with impulsive and aggressive behavior in people. There is a cause and effect relationship between inflammation and IED.

A number of methods are available for the treatment of Intermittent Explosive Disorder or IED, such as medication and behavioral therapy. Seeking treatment is important for the patient as opposed to keeping up with their hostile treatment of family and friends. Moreover, inflammation also put people at risk for other medical complications such as heart attack, arthritis and stroke.

One of the latest additions in the field is “Inflammation & Allergy - Drug Targets”, a popular research journal published by one of the leading STM publishers in the industry, Bentham Science Publishers. The journal aims to cater to the discovery, identification, characterization and validation of novel human drug targets for anti-inflammation and allergy drug discovery continues to grow, this journal has become essential reading for all pharmaceutical scientists involved in drug discovery and development.

Continue